ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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BEEF ALLERGY


Key Allergens

There are 12 allergens associated with cows, 3 of them relate to an allergy to consumption of meat (rather than to the milk they produce). One of the allergenic proteins is a lipocalin, an allergen common in pet hair allergies. These proteins transport molecules like lipids and steroids around the body.

Serum albumin proteins are responsible for allergic reactions to mammalian meat in general, if allergic to many types of red meat then you may have Alpa-gal Syndrome.

If sensitised to Bovine Serum Albumin (BSA) only, then you may have issues with eating beef and drinking cow's milk.


Associated Syndromes

An allergic syndrome associated with beef allergy is Alpha-gal syndrome. This is when a person is bitten by a tick. The tick passes on a carbohydrate called galactose-alpha-1,3-galactose (also known as alpha-gal). This carbohydrate causes an immune reaction to make IgE antibodies. This is an unusual syndrome as it is caused by a carbohydrate and not a protein and because it often causes delayed IgE allergic reactions unlike classic IgE reactions which are very quick.

Cross Reactivity

In extreme cases there may be some cross reactivity between other foods containing serum albumin proteins. These foods include other meats such as pork and lamb.

This is also the case for Alpha-gal Syndrome, other mammalian and bird meats containing serum albumin may cause delayed IgE reactions.

About 10% of cow's milk allergy sufferers will also react to beef when consumed.


Resources

Websites

Science Direct - Galactose-alpha-1-3-galactose

Allergen Encyclopedia - Beef

DermNet NZ - Tick bite induced red meat allergy

Anaphylaxis Campaign - Tick bites and allergic reactions to red meat

ACAAI - Meat Allergy

CDC - Alpha-gal Allergy


Articles and Journals

Milk and cow’s meat allergy in a child: A clinical case

Red meat allergy in children and adults, 2019

The alpha-Gal syndrome: new insights into the tick-host conflict and cooperation, 2019

Galactose-alpha-1,3-galactose sensitization is a prerequisite for pork-kidney allergy and cofactor-related mammalian meat anaphylaxis, 2014

Bovine Serum Albumin: a double allergy risk, 2013

Beef allergy: a review of 12 cases, 2003

Anaphylaxis to cow's milk and beef meat proteins, 2002

Beef allergy in children with cow's milk allergy; cow's milk allergy in children with beef allergy, 2002

Beef allergy in children, 2000

Molecular and crystal properties of Bos d 2, an allergenic protein of the lipocalin family, 1998

cDNA cloning and protein analysis of a bovine dermal allergen with homology to psoriasin, 1995



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.



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