ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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CASSAVA ALLERGY


Key Allergens

Cassava is a root vegetable from the Manihot esculenta plant and is known interchangeably as yuka and manioc. It is most commonly eaten in Africa and Central and South America, but is becoming increasingly more popular worldwide.

Cassava is in the Euphorbiaceae family of plants. This family also includes castor beans and the rubber tree plant Hevea brasiliensis the main plant responsible for latex allergies.

Man e 5 is the main protein in cassava that causes allergic reactions. This is a glutamic acid rich protein, similar in structure to hevein.

Hevein's role in plants is in plant defense, it is an important allergen as it is not easily broken down by heat or processing and can still cause an allergic reaction.

Cassava can be ground to make tapioca flour, this is used in breads and as a thickening agent. Tapioca flour is also the main ingredient in boba or bubble tea, this South East Asian drink has spread to most of the world.



Associated Syndromes

Cassava allergy can be linked to Latex Food Syndrome as the main allergen is similar in structure to hevein, which can cause problems in people with a latex allergy.

Cross Reactivity

Those with a sensitivity to hevein or chitinase may have linked allergies to foods which contain high levels of chitinase, like avocado, banana, chestnuts, corn (maize), kiwi, papaya, pomegranate and tomatoes.



Resources

Websites

Science Direct - Hevein

Allergy Asthma Network - Latex Allergy

Latex-Fruit Syndrome and Class 2 Food Allergy


Articles and Journals

Food allergy to wheat, soybean and cassava in Benin: Literature Review, 2016

Latex-fruit syndrome in Italian children and adolescents with natural rubber latex allergy, 2013

Novel allergens from ancient foods: Man e 5 from manioc (Manihot esculenta Crantz) cross reacts with Hev b 5 from latex, 2013

Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy, 2011

Allergic reactions to manioc (Manihot esculenta Crantz): Identification of novel allergens with potential involvement in latex-fruit syndrome, 2011

Allergy to cassava: a new allergenic food with cross-reactivity to latex, 2007



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