Key Allergens

In Europe celery is listed as a top 14 allergen which needs to be labelled in packaged food.

There are 6 allergens associated with celery allergy - the main allergen in celery is Api g 1 which is similar in shape to the Bet v 1 allergens which can cause oral allergy type symptoms.

Two of the proteins found in celery are lipid transfer proteins, Api g 2 and 6.

Api g 4 is a profilin protein, these are panallergens and found in many fruits and vegetables.

Celery also contains chemicals called furanocoumarins, these can act as a contact allergen. When they come in contact with the skin it can become more sensitive to sunlight which can cause blistering. This is more common as an occupational allergy with people who pick, pack and process celery. This is known as phototoxicity. Additionally there have been case reports of ingestion of celery causing severe sunburn and blistering in rare cases.

Associated Syndromes

You may have Pollen-Food Allergy Syndrome if you suffer from celery allergy with oral allergy symptoms to 3 or more of the foods mentioned in cross reactivity section.

The lipid transfer proteins in celery may cause problems if you suffer from LTP Syndrome.

Allergy to celery is commonly linked to Celery-Mugwort-Spice Syndrome as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.

There is a link between celery and Latex Food Syndrome. The plant involved in latex allergy Hevea brasiliensis, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.

Cross Reactivity

If sensitised to birch pollen you may have Pollen Food Allergy Syndrome and may also react to apple, kiwi, pear, peach, plum, nectarine, apricots, cherries, tomato, celery, potato, parsnip, pepper, dill, cumin, peas, coriander, fennel, hazelnut, walnut, almonds, peanuts, lentils and beans.

If sensitised to alder pollen you may also react to apple, cherry, peach, pear, parsley, celery, almonds and hazelnuts.

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

Other foods containing plant profilins are kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, melon, strawberry, soya, barley, walnut, lychee, lupin, apple, banana, date, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.



Allergen Encyclopedia - Celery

DermNet NZ - Celery

Anaphylaxis Campaign - Celery Allergy

Allergy information for: Celery, Celeriac (graveolens)

Types of Food Allergy

Oral Allergy Syndrome (OAS) or Pollen Fruit Syndrome (PFS)

Worcester university Pollen Calendar

Articles and Journals

Identification of a defensin as novel allergen in celery root: Api g 7 as a missing link in the diagnosis of celery allergy? 2021

Phototoxic and Photoallergic Contact Reactions, 2020

Food allergy to apple, peach and celery in atopic dermatitis patients, analysis of sensitisation to molecular components, 2020

Can patients with oral allergy syndrome be at risk of anaphylaxis?, 2020

Pollen-food allergy syndrome in children, 2020

Clinical reactivity of celery cultivars in allergic patients: Role of Api g 1, 2018

Sensitization Prevalence, Antibody Cross-Reactivity and Immunogenic Peptide Profile of Api g 2, the Non-Specific Lipid Transfer Protein 1 of Celery, 2011

The prevalence of positive reactions in the atopy patch test with aeroallergens and food allergens in subjects with atopic eczema: a European multicenter study, 2004

Severe Phototoxic Burn Following Celery Ingestion, 1990

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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