There are 3 allergens associated with coffee allergy. Cof a 1 is a chitinase protein. Chitinase proteins are usually associated with Latex Food Syndrome
, but in this case the allergen is an inhalant allergen and not a food allergen, so does not need to be avoided if suffering from this syndrome.
Cof a 2 and Cof a 3 are both metallothionein proteins. Again these are inhalant allergens and not food allergens and they are used in the plant to bind metals such as zinc.
Allergy to chitinase proteins has been linked to Latex Food Syndrome.
Coffee allergy has been linked to asthma, rhinoconjunctivitis and atopic dermatitis, especially in patients who work with coffee occupationally.
Other foods containing chitinase proteins are chestnuts, banana, avocado, pomegranate and maize. Other plants containing chitinases which are considered to be inhalant allergens are cockroaches and dust mites.
Allergen Encyclopedia - Coffee
Caffeine Allergy & Coffee Intolerance: What You Need to Know
Do I Have a Coffee Allergy?
Articles and Journals
Identification of two metallothioneins as novel inhalative coffee allergens cof a 2 and cof a 3, 2015
Cof a 1: identification, expression and immunoreactivity of the first coffee allergen, 2012
Coffee Anyone? Are You at Risk of Allergy? 2012
Helminthic infection as a factor in new-onset coffee allergy in a father and daughter, 2008
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