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COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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DATE ALLERGY


Key Allergens

Date Palms are a plant in the Arecaceae family, also commonly known as palm trees. The fruits of this particular plant are called dates.

The key allergen found in dates is a profilin called Pho d 2.

Profilins are small proteins involved in the assembly of actin filaments. Actin filaments in plants determine the shape and movement of the cell’s surface.

Profilin proteins are considered to be minor panallergens. They are less commonly associated with allergy than lipid transfer proteins and seed storage proteins, but have become more studied in recent years due to the possibility of cross reactivity.

An intolerance to dried dates could be one of two things. Dates contain sulphites, a preservative added to dried fruit to give it a longer shelf life. They also have naturally high levels of salicylates which can cause food intolerance symptoms.


Associated Syndromes

Allergy to dates is sometimes linked to Celery-Mugwort-Spice Syndrome as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.

There is also a link between dates and Latex Food Syndrome. The plant involved in latex allergy Hevea brasiliensis, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.


Cross Reactivity

Other plants containing profilin proteins are kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, muskmelon, carrot, strawberry, soya beans, barley, walnut, lychee, lupin, apple, banana, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.

Resources

Websites

Food Allergy Canada Factsheet on Sulphites

Allergy UK Factsheet on Sulphites

Allergen Encyclopedia

Allergy information for: Date (Phoenix dactylifera)


Articles and Journals

Charting novel allergens from date palm pollen (Phoenix sylvestris) using homology driven proteomics, 2017

Clinical profile of a Mediterranean population sensitised to date palm pollen (Phoenix dactylifera). A retrospective study, 2011

Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen, 2008

Pho d 2, a major allergen from date palm pollen, is a profilin: cloning, sequencing, and immunoglobulin E cross‐reactivity with other profilins, 2005

Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome, 2002

Allergy to date fruits: characterization of antigens and allergens of fruits of the date palm (Phoenix dactylifera L.), 2001



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