Date Palms are a plant in the Arecaceae
family, also commonly known as palm trees. The fruits of this particular plant are called dates.
The key allergen found in dates is a profilin called Pho d 2.
Profilins are small proteins involved in the assembly of actin filaments. Actin filaments in plants determine the shape and movement of the cell’s surface.
are considered to be minor panallergens. They are less commonly associated with allergy than lipid transfer proteins and seed storage proteins, but have become more studied in recent years due to the possibility of cross reactivity.
An intolerance to dried dates could be one of two things. Dates contain sulphites
, a preservative added to dried fruit to give it a longer shelf life. They also have naturally high levels of salicylates which can cause food intolerance symptoms.
Allergy to dates is sometimes linked to Celery-Mugwort-Spice Syndrome
as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.
There is also a link between dates and Latex Food Syndrome
. The plant involved in latex allergy Hevea brasiliensis
, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.
Other plants containing profilin proteins are kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, muskmelon, carrot, strawberry, soya beans, barley, walnut, lychee, lupin, apple, banana, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.
Food Allergy Canada Factsheet on Sulphites
Allergy UK Factsheet on Sulphites
Allergy information for: Date (Phoenix dactylifera)
Articles and Journals
Charting novel allergens from date palm pollen (Phoenix sylvestris) using homology driven proteomics, 2017
Clinical profile of a Mediterranean population sensitised to date palm pollen (Phoenix dactylifera). A retrospective study, 2011
Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen, 2008
Pho d 2, a major allergen from date palm pollen, is a profilin: cloning, sequencing, and immunoglobulin E cross‐reactivity with other profilins, 2005
Cross-reactivities between date palm (Phoenix dactylifera L.) polypeptides and foods implicated in the oral allergy syndrome, 2002
Allergy to date fruits: characterization of antigens and allergens of fruits of the date palm (Phoenix dactylifera L.), 2001
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