There are 8 allergens associated with dogs, they are all allergens which affect the airways.
Can f 1, 2, 4 and 6 are all lipocalin proteins. These proteins are the most likely candidate for your allergy to pet hair. These proteins transport molecules like lipids and steroids around the body.
Can f 3 is a serum albumin protein, people who are allergic to this protein are more likely to be allergic to other mammals and very rarely can become allergic to eating mammalian meats such as beef, chicken and pork, which also contain these proteins.
Allergy to dog dander is strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.
A dog allergy can be strongly linked to other animal allergies due to the lipocalin proteins. There is evidence of cross reactivity due to this protein with cockroaches, cows, cats, guinea pigs, horses, hamsters, mice, rabbits and rats.
Allergy UK - Your Quick Guide to Pet Allergy
Allergen Encyclopedia - Dog Dander
Healthline - Am I allergic to my dog?
Articles and Journals
Analysis of allergen profile in patients sensitized to canine allergen and potential Can f 5 cross-reactivity with human PSA, 2021
Allergenicity of dogs A pilot study into Can f1 levels in hair and coat of dogs measured over a short period of time: stability of levels of allergen shed, 2021
Component-resolved diagnostics in pet allergy: Current perspectives and future directions, 2021
Dog Ownership at 3 Months of Age is Associated With Protection Against Food Allergy, 2019
Characterization of the dog lipocalin allergen Can f 6: the role in cross-reactivity with cat and horse, 2012
Prostatic kallikrein: a new major dog allergen, 2009
Molecular and immunological characterization of Can f 4: a dog dander allergen cross-reactive with a 23 kDa odorant-binding protein in cow dander, 2010
Does early exposure to cat or dog protect against later allergy development?, 1999
Molecular characterization of dog albumin as a cross-reactive allergen, 1994
Affinity purification of a major and a minor allergen from dog extract: serologic activity of affinity-purified Can f I and of Can f I-depleted extract, 1991
Purification and characterization of the major dog allergen, Can f I, 1991
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