ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

DUST MITE ALLERGY


Key Allergens

There are 4 dust mite species in the World Health Organization Allergy database. Dermatophagoides farinae is also known as the American House Dust Mite which has 36 recognised airway allergens.

Dermatophagoides microceras has 1 allergen, a cysteine protease called Der m 1.

The European House Dust Mite, Dermatophagoides pteronyssinus has 30 recognised allergens and Euroglyphus maynei another species of house dust mite has just 5.

Cysteine Protease is a protein found in all species of dust mites and may be one of the proteins most patients are allergic to.

Other allergens associated with dust mites are cyclophilin proteins, tropomyosin and chitinase.

Associated Syndromes

Allergy to dust mites is strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.

Some species of dust mites contain chitinase, which is linked to Latex Allergy.

Cross Reactivity

The tropomyosin proteins in dust mites are also found in crustaceans and molluscs and are also linked to allergies to other insects like cockroaches, termites and midges.

Cockroaches also contain chitinase proteins which can cause an inhalant reaction. Foods containing chitinase include corn, avocado, banana, pomegranate, coffee and chestnuts.

Cysteine Protease is also found in ragweed pollen. They are also found in foods like kiwi, papaya and potato.

Other plants containing cyclophilin include peanut, birch tree, moulds and fungus (including magic mushrooms) and tomatoes.

Resources

Websites

Allergy UK - House Dust Mite Allergy

Patient UK - House Dust Mite Allergy

DermNet NZ - House Dust Mite

Asthma and Allergy Foundation of America - House Dust Mite Allergy

Healthline - Dust Mite Allergies

Science Direct - Euroglyphus maynei

Science Direct - Dermatophagoides

Allergen Encyclopedia - American House Dust Mite

Allergen Encyclopedia - European House Dust Mite


Articles and Journals

House Dust Mite Allergy and the Der p1 Conundrum: A Literature Review and Case Series, 2021

Satisfaction of allergic patients treated with house dust mite sublingual immunotherapy, 2021

House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins, 2021

Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite, 2021

House dust mite-specific immunotherapy alters the natural course of atopic march, 2020

CyPE is an essential element of allergen cyclophilin family, 2020

Correlation of acidic mammalian chitinase expression with disease severity in patients with moderate/severe persistent allergic rhinitis, 2020

House Dust Mite Allergy Under Changing Environments, 2019

Emerging roles of the protease allergen Der p 1 in house dust mite–induced airway inflammation, 2018



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