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COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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FENUGREEK ALLERGY


Key Allergens

Fenugreek (also known as methi) is a legume in the Fabaceae family of plants which also includes tamarind, soya, peanuts, peas and chickpeas.

There are no recorded allergens for fenugreek by the World Health Organization (WHO), because there have not been enough study into allergic effects from this food. If you are interested in what is needed by the WHO before they add an allergen to their allergen database you can check that out HERE.

Studies have shown that fenugreek contains 2S seed storage proteins, 7S seed storage proteins (also known as vicilin) and 11S seeds storage proteins (also known as legumin). These groups of proteins are commonly found in nuts, seeds and legumes.

A PR-10 plant pollen protein ('PR' meaning 'pathogenesis related' - related to plant defence against plant pathogens) has also been identified in fenugreek. These proteins are Bet v 1 -like proteins and if allergic to this particular protein can get oral allergy type symptoms.


Associated Syndromes

Fenugreek contain Bet v 1 like proteins, so could be linked to Pollen Food Allergy Syndrome. You may have Pollen-Food Allergy Syndrome if you suffer from fenugreek allergy with oral allergy symptoms to 3 or more of the foods mentioned in the cross reactivity section.

Cross Reactivity

Other food containing 2S albumin seed storage proteins are cashews, peanuts, brazil nuts, mustard seed, rapeseed, turnip, chickpeas, hazelnuts, pistachio, buckwheat, soya, sunflower seeds, walnuts, kiwi, castor beans and sesame seeds.

Other foods containing 7S and 11S proteins not mentioned in the list above are lupin, lentils, macadamia, peas and mung beans.

If sensitised to Birch pollen you may have Pollen Food Allergy Syndrome and may also react to apple, carrot, kiwi, pear, peach, plum, nectarine, apricots, cherries, tomato, celery, potato, parsnip, pepper, cumin, peas, dill, fennel, hazelnut, walnut, almonds, coriander, peanuts, lentils and beans.


Resources

Websites

Allergen Encyclopedia - Fenugreek

Anaphylaxis Campaign - Fenugreek (Also Known as Methi)


Articles and Journals

Fenugreek: A hidden allergen to consider in peanut allergic patients, 2019

Fenugreek Anaphylaxis in a Pediatric Patient, 2018

Cross‐allergic Reactions to Legumes in Lupin and Fenugreek‐Sensitized Mice, 2012

Anaphylactic Reactions in Mice with Fenugreek Allergy, 2011

Characterization of potential allergens in fenugreek (Trigonella foenum graecum) using patient sera and MS-based proteomic analysis, 2010

Allergy to Fenugreek (Trigonella foenum graecum), 1997



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.


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