ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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HORSE HAIR ALLERGY


Key Allergens

There are 6 allergens associated with an allergy to horses, this includes their hair, dander (which is flakes of dry skin), urine and saliva.

Equ c 1 and Equ c 2 are lipocalin proteins, in other animal dander allergies this is the protein that most individuals react to. These proteins transport molecules like lipids and steroids around the body.

Equ c 3 is a serum albumin protein, people who are allergic to this protein are more likely to be allergic to other mammals and very rarely can become allergic to eating mammalian meats such as beef, chicken and pork, which also contain these proteins.

Equ c 6 is a lysozyme which is a contact allergen and is also found in donkeys and chickens.

Curly horses are often said to be hypoallergenic, but studies are divided, some say that spending time with curly horses can reduce allergy symptoms over time. Other studies have shown that curly horse hair still contains lipocalin proteins that are a trigger for horse hair allergies.


Associated Syndromes

Allergy to horse hair is strongly strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.

Cross Reactivity

A horse allergy can be strongly linked to other animal allergies due to the lipocalin proteins. There is evidence of cross reactivity due to this protein with cockroaches, cows, dogs, guinea pigs, hamsters, cats, mice, rabbits and rats.

In extreme cases there may be some cross reactivity between other foods containing serum albumin proteins. These foods include meats such as beef, pork and chicken.

These food lists are not exhaustive, the most up to date information is on the Cross Reactivity Tool.




Resources

Websites

Healthline - Horse Allergy: Yes, it's a thing

Allergen Encyclopedia - Horse

Science Direct - Lipocalin

Allergy UK - Pet Allergy Factsheet


Articles and Journals

Proteomic analysis of horse hair extracts provides no evidence for the existence of a hypoallergenic Curly Horse breed, 2024

Creatures Great and Small: Horse and Dog Allergy Cross-Reactivity, 2024

Horse allergy: Curly Horses can mediate immune tolerance, 2024

Why is Pet (Cat/Dog) Allergen Immunotherapy (AIT) Such a Controversial Topic? Current Perspectives and Future Directions, 2024

Component-Resolved Diagnosis Based on a Recombinant Variant of Mus m 1 Lipocalin Allergen, 2023

The diversity of lipocalin receptors, 2022

Exotic pet allergy, 2019

Diagnosis of Allergy to Mammals and Fish: Cross-Reactive vs. Specific Markers, 2017

Horse Allergy: Curly Horses Allow Horse Allergic Riders To Ride Again, 2015

Allergy to uncommon pets: new allergies but the same allergens, 2013

Characterization of the dog lipocalin allergen Can f 6: the role in cross-reactivity with cat and horse, 2012

Anaphylaxis as a Manifestation of Horse Allergy, 2009

Anaphylaxis after a horse bite, 2005

Clinical experience with specific immunotherapy to horse dander, 2002



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.


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