LTP SYNDROME
Key Points
Lipid Transfer Proteins (LTP) are found in many types of plants. You may be allergic to all or some of the foods mentioned in the cross reactivity section.
LTP Syndrome can be confused with
Pollen Food Allergy Syndrome (PFAS) as there is a crossover of common trigger foods. In general PFAS symptoms are less severe and give oral allergy type symptoms. Reactions to LTP are more severe and a reaction is elicited from foods that have been cooked.
The articles below all relate generally to LTP syndrome - please visit each food page for resources on specific foods.
Cross Reactivity
Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.
Resources
Websites
Anaphylaxis Campaign - Lipid Transfer Proteins (LTP Syndrome)
British Dietetic Association - PFAS vs LTP Syndrome
Articles and Journals
Does the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins? 2021
The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area, 2021
Non-specific lipid-transfer proteins: Allergen structure and function, cross-reactivity, sensitization, and epidemiology, 2021
The diagnosis and management of allergic reactions in patients sensitized to non-specific lipid transfer proteins, 2021
Nickel allergy in lipid transfer protein sensitized patients: Prevalence and clinical features, 2020
Lipid Transfer Protein allergy in the United Kingdom: Characterization and comparison with a matched Italian cohort, 2019
Anaphylaxis caused by lipid transfer proteins: an unpredictable clinical syndrome, 2018
How relevant is panallergen sensitization in the development of allergies?, 2016
Asymptomatic LTP sensitisation is common in plant-food allergic children from the Northeast of Spain, 2016
In patients with LTP syndrome food-specific IgE show a predictable hierarchical order, 2014
Lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant‐foods and pollens, 2012
Molecular allergology in practice: an unusual case of LTP allergy, 2011
Let me know if you found any of these interesting or useful.
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