ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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LEMON ALLERGY


Key Allergens

The allergen associated with lemon allergy is called Cit l 1.

Cit l 1 is a Lipid Transfer Protein (LTP), these proteins are resistant to heat and are found in many types of plants. Patients suffering from a more severe allergy to cooked fruit may be sensitised to this group of proteins.

Lemons also contain limonene, which is a component of the oils found in the peel of certain fruits. Limonene is a well known skin irritant - so may cause sufferers to react to the skin whilst being able to eat or drink the fruit.

There is an increasing amount of research into citrus seed allergy - it has been suggested that some allergic reactions have been triggered not by the fruit or peel, but by accidental consumption of the seeds. These allergic reactions may be triggered by proteins found in more commonly eaten seeds (like sunflower and pumpkin seeds) - seed storage proteins.


Associated Syndromes

You may be suffering from LTP Syndrome if you have reactions to various fruits, vegetables and nuts and your reactions continue to be severe after you have discarded the peel and have cooked the food.

Eating lemons is also associated with phytodermatitis. This is a skin condition that occurs when a person gets the juice from the fruit on the skin and doesn't wash it off. The furocoumarins in the juice of the fruit are activated by the sun and cause an itchy rash on the skin.

Cross Reactivity

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

Lemon allergens have shown cross-reactivity with the major peach allergen Pru p 3.


Resources

Websites

Science Direct - Lipid Transfer Proteins

Allergen Encyclopedia - Lemon

Lipid Transfer Proteins (LTP Syndrome)

Allergy to Fruit - Anaphylaxis Campaign

Do You Have a Citrus Allergy? Learn the Symptoms

What You Need to Know About Allergic Reaction to Essential Oils

DermNet NZ - Phytodermatitis

DermNet NZ - Lemon


Articles and Journals

Evidence of mold allergy in patients with allergic reactions to packaged juice, 2020

Lemon seed allergy: a case presentation, 2020

Allergy to lemon: case of oral allergic syndrome associated with allergic otitis media and labyrinthitis in a patient with polysensibilization and multiple manifestations of allergy, 2019

Lipid Transfer Protein allergy in the United Kingdom: Characterization and comparison with a matched Italian cohort, 2019

Allergy to oxidized limonene and linalool is frequent in the U.K, 2014

Allergy to citrus juice, 2013

Citrus Allergy from Pollen to Clinical Symptoms, 2013

Anaphylaxis to lemon soap: citrus seed and peanut allergen cross-reactivity, 2007

Lipid transfer proteins and allergy to oranges, 2005



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.


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