ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

PINEAPPLE ALLERGY


Key Allergens

The key allergens in pineapple are Ana c 1 and Ana c 2.

Ana c 1 is a profilin protein, this is a panallergen known to sometimes cause allergy reactions in multiple foods containing similar proteins.

Ana c 2 is called bromelain. This has been known to cause IgE mediated allergies and symptoms most often related to the respiratory system. This biochemical is commonly extracted from pineapple and used in cosmetics and food production where it is frequently used as a meat tenderiser (which is why your lips may tingle when eating pineapple).

Bromelain is a papain, which is the active constituent in latex-related fruits, this is the protein which can cause cross reactivity with latex.

Associated Syndromes

If you suffer from pineapple allergy and other foods mentioned in the cross reactivity section below you may suffer from Latex Food Syndrome.

Cross Reactivity

If sensitised to pineapple you may also be allergic to banana, papaya, avocado, chestnut, corn, kiwi, pomegranate and latex.

Other foods containing plant profilin proteins include pineapple, kiwi, celery, peanut, chilli, watermelon, muskmelon, hazelnut, orange, carrot, strawberry, soya beans, barley, walnut, lychee, lupin, apple, banana, dates, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.

Resources

Websites

Allergen Encyclopedia - Pineapple

Science Direct - Papain

Allergy information for: Pineapple (Ananas comosus )

https://allergyhq.com/pineapple-allergy

https://www.healthline.com/health/pineapple-allergy


Articles and Journals

The many flavors of pineapple reactions, 2019

Misleading Allergens in the Diagnosis of Latex Allergy: Profilin and Cross-Reactive Carbohydrate Determinants, 2018

Prevalence of oral allergy syndrome in children with allergic diseases, 2017

IgE reactivity to profilin in pollen-sensitized subjects with adverse reactions to banana and pineapple, 2002

Allergy to latex and papain, 1995

Systemic allergic reaction and diarrhoea after pineapple ingestion, 1993

Asthma caused by bromelain: an occupational allergy, 1988

Allergic reactions, including asthma, to the pineapple protease bromelain following occupational exposure, 1979



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FURTHER READING RECOMMENDATIONS

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