There are 3 allergens thought to cause reactions in pomegranates, called Pun g 1, Pun g 7 and Pun g 14.
Pun g 1 is a lipid transfer protein (LTP). Most cases of pomegranate allergy are linked to this protein.
Pun g 7 is a gibberellin, these are plant growth hormones.
Pun g 14 is a chitinase protein. This is a plant derived enzyme made by plants naturally to act as a defence against fungal attacks.
Pomegranate allergy is seen in conjunction with allergies to other foods presenting as Latex Food Syndrome, which is caused by the body confusing the proteins it encounters in food to that of latex proteins to which it is already sensitised.
LTP's are a group of proteins which can cause more serious allergic reactions in patients, you may suffer from LTP Syndrome if you suffer IgE type allergy symptoms to foods mentioned in the cross reactivity section below.
Those with a sensitivity to chitinase may have linked allergies to foods which contain high levels of chitinase like chestnuts, banana, avocados, papaya, maize (corn), kiwi and tomatoes.
Foods linked to LTP Syndrome are hazelnuts, almonds, walnuts, apples, dried fruit, lettuce and tomatoes. Symptoms are more intense if food is dried or concentrated.