ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

PORK ALLERGY


Key Allergens

There is one allergen associated with an allergy to pork and that is Sus s 1, this is a serum albumin protein.

Associated Syndromes

There is some evidence of cross reactivity between eating pork and allergic reaction to cat skin. This is known as Pork-Cat Syndrome.

A more recent and commonly known syndrome associated with pork allergy is Alpha-gal syndrome. This is when a person is bitten by a tick. The tick passes on a carbohydrate called galactose-alpha-1,3-galactose (also known as alpha-gal). This carbohydrate causes an immune reaction to make IgE antibodies. This is an unusual syndrome as it is caused by a carbohydrate and not a protein and because it often causes delayed IgE allergic reactions unlike classic IgE reactions which are very quick.

Cross Reactivity

In extreme cases there may be some cross reactivity between other foods containing serum albumin proteins. These foods include other meats such as beef and chicken.

This is also the case for Alpha-gal Syndrome, other mammalian and bird meats containing serum albumin may cause delayed IgE reactions.

Resources

Websites

Allergen Encyclopedia - Pork

DermNet NZ - Tick Bite Induced Red Meat Allergy

Anaphylaxis Campaign - Tick bites and allergic reactions to red meat

ACAAI - Meat Allergy

CDC - Alpha-gal Allergy


Articles and Journals

Recurrent urticaria caused by specific cat serum albumin IgE cross-reacting with pork serum albumin, 2020

Red meat allergy in children and adults, 2019/a>

What Does a Red Meat Allergy Have to Do With Anesthesia? Perioperative Management of Alpha-Gal Syndrome, 2019

The alpha-Gal syndrome: new insights into the tick-host conflict and cooperation, 2019

Galactose-alpha-1,3-galactose sensitization is a prerequisite for pork-kidney allergy and cofactor-related mammalian meat anaphylaxis, 2014

Initial description of pork-cat syndrome in the United States, 2013

Cat-pork syndrome: a case report with a thee years follow-up, 2006

Allergic cross-reactions between cat and pig serum albumin. Study at the protein and DNA levels, 1997

The pork-cat syndrome or crossed allergy between pork meat and cat epithelia, 1994



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