ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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RAT ALLERGY


Key Allergens

Rats are in the Rodentia family of animals which also includes hamsters, mice and guinea pigs.

The allergen associated with an allergy to rats is a protein called lipocalin. These proteins transport molecules like lipids and steroids around the body.

Most pet dander allergies are down to lipocalin proteins (with the exception of cats).


Associated Syndromes

Allergy to rat dander is strongly strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.


Cross Reactivity

A rat allergy can be strongly linked to other animal allergies due to the lipocalin proteins. There is evidence of cross reactivity due to this protein with cockroaches, cows, dogs, guinea pigs, horses, cats, hamsters, mice and rabbitts.


Resources

Websites

Science Direct - Lipocalin

Allergy UK - Pet Allergy


Articles and Journals

In silico analysis of a major allergen from Rattus norvegicus, Rat n 1, and cross-reactivity with domestic pets, 2019

In silico Analysis of Cross Reactivity between Lipocalin of Domestic Animals, 2018

Sensitization and exposure to pets: The effect on asthma morbidity in the United States population, 2018

Anaphylaxis in laboratory workers because of rodent handling: two case reports, 2016

Allergy to furry animals: New insights, diagnostic approaches, and challenges, 2015

Analysis of allergens in rat fur and saliva, 2001

Mapping of IgE binding regions in the major rat urinary protein, alpha 2u-globulin, using overlapping peptides, 1999

Purification and identification of allergenic alpha (2u)-globulin species of rat urine, 1996



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook, Instagram or Twitter - links at the bottom of the page.

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