ALLERGY RESOURCES

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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RYE ALLERGY


Key Allergens

There are 3 allergens associated with a allergy to rye. Two are airway allergens and one is a food allergy called Sec c 20 which a gamma secalin protein.

Secalin proteins are prolamins, storage proteins found in cereal crops which have the ability to trigger coeliac disease symptoms. Collectively these proteins are known as gluten.

Sec c 5 is a grass pollen allergen and Sec c 38 is dimeric alpha-amylase/trypsin inhibitor, both are pollen allergens.

Associated Syndromes

The protein associated with rye allergy is linked to Exercise Induced Anaphylaxis, more specifically wheat dependent exercise induced anaphylaxis.

Coeliac disease is not an allergic condition, but is triggered by gluten found in rye to which sensitive individuals may react.

Cross Reactivity

If you react to wheat, especially with anaphylaxis symptoms after exercising then you may want to also avoid consumption of rye.

Rye is in the Poales order of plants, so there may be some cross reactivity with other foods in the group such as wheat, barley and maize.

Wheat also contains dimeric alpha-amylase/trypsin inhibitor, so there may be some cross reactivity if you have airway reactions to rye.


Resources

Websites

Science Direct - Secalin

Allergen Encyclopedia - Rye

DermNet NZ - Aeroallergens

Allergy information for: Rye (Secale cereale)


Articles and Journals

Celiac Disease and Sensitization to Wheat, Rye, and Barley: Should We Be Concerned? 2021

Comprehensive proteome analysis of bread deciphering the allergenic potential of bread wheat, spelt and rye, 2021

Rye flour allergens: an emerging role in baker's asthma, 2008

Rye gamma-70 and gamma-35 secalins and barley gamma-3 hordein cross-react with omega-5 gliadin, a major allergen in wheat-dependent, exercise-induced anaphylaxis, 2001

Life-threatening, recurrent anaphylaxis caused by allergy to gliadin and exercise, 1997

Immunologic cross-reactivity among cereal grains and grasses in children with food hypersensitivity, 1995



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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