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COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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TANGERINE ALLERGY


Key Allergens

Tangerine oranges are also sometimes known as 'mandarin'. The allergen associated with tangerine allergy is called Cit r 3.

Cit r 3 is a Lipid Transfer Protein (LTP), these proteins are resistant to heat and are found in many types of plants. Patients suffering from a more severe allergy to cooked fruit may be sensitised to this group of proteins.

There is a case study (link at the bottom) of anaphylaxis due to the consumption of tangerine seeds - most likely a cross reaction from a nut allergy (as there are commonly seed storage proteins in the seeds of fruits). This is a very rare occurrence tangerines and oranges are not usually considered to be cross reactive with tree nuts.

Associated Syndromes

You may be suffering from LTP Syndrome if you have reactions to various fruits, vegetables and nuts and your reactions continue to be severe after you have discarded the peel and have cooked the food.

You may have allergic contact dermatitis if you have skin problems after coming into contact with tangerine essential oils or are sensitive to the chemicals in the peel.

Cross Reactivity

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

Orange allergens have shown cross-reactivity with the major peach allergen Pru p 3.

Resources

Websites

Allergen Encyclopedia - Oranges

DermNet NZ - Contact Dermatitis to Essential Oils

Lipid Transfer Proteins (LTP Syndrome)

Allergy to Fruit - Anaphylaxis Campaign

Do You Have a Citrus Allergy? Learn the Symptoms

What You Need to Know About Allergic Reaction to Essential Oils


Articles and Journals

Lemon seed allergy: a case presentation, 2020

Co-sensitization to the fruit seeds and raw potato in children with cashew nut allergy, 2020

Lipid Transfer Protein allergy in the United Kingdom: Characterization and comparison with a matched Italian cohort, 2019

Citrus Allergy from Pollen to Clinical Symptoms, 2013

Anaphylaxis caused by tangerine seeds, but no tangerine fruit, 2008

Anaphylaxis to lemon soap: citrus seed and peanut allergen cross-reactivity, 2007

Anaphylaxis from Mandarin (Citrus reticulata): Identification of Potential Responsible Allergens, 2007

Lipid transfer proteins and allergy to oranges, 2005



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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