COBALT ALLERGY
Key Allergens
Cobalt is a metal which is commonly used as a binding metal in jewellery and household objects like cutlery.
Cobalt allergy has also been noted after transplantation surgery, mostly associated with hip and knee replacements and in dental procedures.
Cobalt can also be found in cosmetics, hair dyes and inks, but it mostly affects people who have occupational contact with the metal.
It is a metallic element and important constituent of vitamin B12, so it may also be found in B12 supplements.
Associated Syndromes
Cross Reactivity
Cross reactivity to
chrome and nickel is commonly seen in patients who are allergic to cobalt.
Resources
Websites
DermNet NZ - Cobalt Allergy
Science Direct - Cobalt
Allergy to Vitamin B12
Cobalt Allergy, what is it?
Cobalt - Dermatitis Academy
Articles and Journals
Overt nickel and cobalt hypersensitivity after pipeline embolization device placement: A case report, 2024
Understanding immune-mediated cobalt/chromium allergy to orthopaedic implants: a meta-synthetic review, 2024
Nickel, cobalt, and chromium in nail sticker and tip products in Korea, 2023
Patch Testing With Cobalt in Adults: A North American Contact Dermatitis Group Experience, 2023
Cobalt nanoparticles cause allergic contact dermatitis in humans, 2023
Is Allergy to Titanium Bone Fixation Plates a Problem? 2022
Chromium and cobalt release from metallic earrings from the Danish market, 2021
Experimental evaluation of nickel and cobalt release from tools and self-reported prevalence of nickel and cobalt allergy in the German hairdressing trade, 2020
Metal allergy in total-joint arthroplasty, 2018
Association between cobalt allergy and dermatitis caused by leather articles – a questionnaire study, 2014
Metal Allergy and Systemic Contact Dermatitis: An Overview, 2012
Prevalence of nickel and cobalt allergy among female patients with dermatitis before and after Danish government regulation: A 23-year retrospective study, 2009
The impact of various patient factors on contact allergy to nickel, cobalt, and chromate, 2006
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