DUST MITE ALLERGY
Key Allergens
There are 4 dust mite species in the World Health Organization Allergy database.
Dermatophagoides farinae is also known as the American House Dust Mite which has 36 recognised airway allergens.
Dermatophagoides microceras has 1 allergen, a cysteine protease called Der m 1.
The European House Dust Mite,
Dermatophagoides pteronyssinus has 30 recognised allergens and
Euroglyphus maynei another species of house dust mite has just 5.
Cysteine Protease is a protein found in all species of dust mites and may be one of the proteins most patients are allergic to.
Other allergens associated with dust mites are cyclophilin proteins, tropomyosin and
chitinase.
Associated Syndromes
Allergy to dust mites is strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.
Some species of dust mites contain chitinase, which is linked to
Latex Allergy.
Cross Reactivity
The tropomyosin proteins in dust mites are also found in crustaceans and molluscs and are also linked to allergies to other insects like cockroaches, termites and midges.
Cockroaches also contain chitinase proteins which can cause an inhalant reaction. Foods containing chitinase include corn, avocado, banana, pomegranate, coffee and chestnuts.
Cysteine Protease is also found in ragweed pollen. They are also found in foods like kiwi, papaya and potato.
Other plants containing cyclophilin include peanut, birch tree, moulds and fungus (including magic mushrooms) and tomatoes.
These allergen lists are not exhaustive, the most up to date information is on the Cross Reactivity Tool.
Resources
Websites
Allergy UK - House Dust Mite Allergy
Patient UK - House Dust Mite Allergy
DermNet NZ - House Dust Mite
Asthma and Allergy Foundation of America - House Dust Mite Allergy
Healthline - Dust Mite Allergies
Science Direct - Euroglyphus maynei
Science Direct - Dermatophagoides
Allergen Encyclopedia - American House Dust Mite
Allergen Encyclopedia - European House Dust Mite
Articles and Journals
Associations between house dust mite concentrations in bedroom dust in Northern China and childhood asthma, rhinitis and eczema, 2024
Clinic and diagnostics of house dust mite allergy, 2023
Specific IgE against the house dust mite allergens Der p 5, 20 and 21 influences the phenotype and severity of atopic diseases, 2023
Sensitization to house dust mite and cockroach may mediate the racial difference in shellfish allergy, 2022
IgE-recognition of the house dust mite allergen Der p 37 is associated with asthma, 2021
House Dust Mite Allergy and the Der p1 Conundrum: A Literature Review and Case Series, 2021
Satisfaction of allergic patients treated with house dust mite sublingual immunotherapy, 2021
House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins, 2021
Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite, 2021
House dust mite-specific immunotherapy alters the natural course of atopic march, 2020
CyPE is an essential element of allergen cyclophilin family, 2020
Correlation of acidic mammalian chitinase expression with disease severity in patients with moderate/severe persistent allergic rhinitis, 2020
House Dust Mite Allergy Under Changing Environments, 2019
Emerging roles of the protease allergen Der p 1 in house dust mite–induced airway inflammation, 2018
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