Key Allergens

Flaxseed is harvested from a plant called Linum usitatissimum, it is in the Linaceae family of plants. Flaxseeds can be used crushed to make linseed oil, which is a vegetable oil. The whole flaxseeds can be used in baking and as a health supplement. The leftover product from linseed oil production is used as animal feed.

Lin u 1 is the name of the allegen in flaxseed. This is a 2S seed storage albumin. These types of proteins are found in many seeds and nuts.

Unrefined linseed or flaxseed oils may have the potential to cause allergic reactions if you suffer from allergies to 2S seed storage proteins. You are less likely to react to refined linseed/flaxseed oils as they are so processed.

Food Intolerances

Food is low in FODMAP Food is low in salicylates Food is low in lectins

In normal low servings flaxseed is a low FODMAP food. FODMAP stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.

Flaxseed is a food low in salicylates. Salicylates have the potential to cause gastrointestinal food intolerance symptoms in people who are sensitive to salicylates.

Flaxseeds are lectin free. Lectins are most commonly found in legumes and are another possible cause of food intolerance. Cooking foods with lectins makes them more digestible and can reduce the symptoms of food intolerance.

You can read more about Food Intolerances on the dedicated Food Intolerance Page.

Associated Syndromes

There are no known syndromes associated with flaxseed allergy at this time.

Cross Reactivity

Other foods containing 2S albumin seed storage proteins are brazil nuts, cashews, peanuts, almonds, mustard seed, rapeseed, turnip, chickpeas, hazelnuts, pistachio, buckwheat, soya beans, sunflower seeds, walnuts, kiwi, castor beans and sesame seeds.

Note that this food list is not exhaustive, the most up to date information is on the Cross Reactivity Tool.



Science Direct - Seed Storage Proteins

Allergen Encyclopedia - Linseed

Allergy information for: Flax seed, linseed (Linum usitatissimum)

Articles and Journals

Oral immunotherapy with sunflower seed butter and a review of seed allergy, 2024

The physicochemical stability and in vivo gastrointestinal digestion of flaxseed milk: Implication of microwave on flaxseed, 2023

Sunflower (Helianthus annuus) Seed Allergy: A Case Series, 2023

Clinical and immunological characterization of perilla seed allergy in children, 2022

Nutritional management of immediate hypersensitivity to legumes in vegetarians, 2022

Allergic reactions to emerging food allergens in Canadian children, 2021

Seed Storage Proteins, 2S Albumin And 11S Globulin, Associated to Severe Allergic Reactions after Flaxseed Intake, 2021

Severe anaphylaxis with emergent allergy to seeds, 2020

Anaphylaxis Induced by Conlinin, a 2S Storage Protein in Flaxseed, 2018

Case report: A first case of flaxseed-induced anaphylaxis in Korea, 2017

Hypersensitivities to sesame and other common edible seeds, 2016

Case report: anaphylaxis caused by linseed included in baked bread, 2014

Flax seed allergy in children: an emerging allergen? 2010

2S Albumin Storage Proteins: What Makes them Food Allergens? 2008

Anaphylaxis to Linum, 2003

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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