MOUSE ALLERGY
Key Allergens
Mice are animals in the Muridae family of rodents. Other animals in this family include gerbils and rats.
There is only 1 allergen associated with an allergy to mice, this includes their hair, dander (which is flakes of dry skin), urine and saliva.
Mus m 1 are lipocalin proteins, in other animal dander allergies this is the protein that most individuals react to. These proteins transport molecules like lipids and steroids around the body.
Symptoms of an allergy to mice might include contact allergic dermatitis, rhinoconjunctivitis, rhinitis and worsening symptoms of asthma.
It can be a difficult allergy to manage as you cannot control the cleanliness of public places like schools and colleges. Dealing with any mice problem you may have at home can reduce your symptoms. This would include regular cleaning, making sure there is not food or crumbs around to be scavenged and blocking off entry points for the rodents.
Associated Syndromes
Allergy to mouse dander is strongly strongly associated with allergic rhinitis as well as asthma, rhinoconjunctivitis and atopic dermatitis.
Cross Reactivity
A mouse allergy can be strongly linked to other animal allergies due to the lipocalin proteins. There is evidence of cross reactivity due to this protein with cockroaches, cows, dogs, guinea pigs, horses, cats, hamsters, rabbits and rats.
Resources
Websites
Allergen Encyclopedia - Mouse
Science Direct - Lipocalin
Allergy UK - Pet Allergy
Articles and Journals
Hypoallergenic animals: A promise of hope for allergic patients? 2024
Component-Resolved Diagnosis Based on a Recombinant Variant of Mus m 1 Lipocalin Allergen, 2023
Update on indoor allergens and their impact on pediatric asthma, 2022
Diversity and complexity of mouse allergens in urine, house dust, and allergen extracts assessed with an immuno-allergomic approach, 2021
Time for Allergists to Consider the Role of Mouse Allergy in Non-Inner City Children with Asthma, 2019
Allergy to Mus m 1: Allergy to Mus m 1: A review of structural, and immunological features, 2019
Exotic pet allergy, 2019
Diagnosis of Allergy to Mammals and Fish: Cross-Reactive vs. Specific Markers, 2017
Diagnostic utility of concentrated Mus m 1 allergen extract in humans, 2014
Allergy to uncommon pets: new allergies but the same allergens, 2013
Mouse (Mus m1) and rat (Rat n1) allergen levels in dust from private and public houses in Strasbourg, France are lower than houses in the U.S.A, 2012
Dual sensitization to rat and mouse urinary allergens reflects cross-reactive molecules rather than atopy, 2009
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