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COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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AUBERGINE ALLERGY


Key Allergens

Aubergine is in the Solanes family of plant which also includes peppers, potatoes and tomatoes. This group of foods is also commonly known as "Nightshades".

In Europe we know this vegetable as Aubergine, in the US and Australia it is known as eggplant and in Asia it is more commonly called brinjal.

The key allergen in aubergine is Sola m 1 which is a profilin protein. This group of proteins are responsible for growth and maintenance in the outer part of the plant. Profilins are the proteins responsible for airway allergies to birch, grass and other pollens.

There is increasing evidence that there are lipid transfer proteins (LTP) in aubergine, again, these proteins are panallergens that cause allergies across multiple foods.


Associated Syndromes

Allergy to aubergine is sometimes linked to Celery-Mugwort-Spice Syndrome as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.

There is a link between aubergine and Latex Food Syndrome. The plant involved in latex allergy Hevea brasiliensis, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.

Aubergine allergy is being increasingly linked to LTP Syndrome.

Cross Reactivity

If sensitised to grass pollen you may also react to melon, watermelon, tomatoes, oranges, potatoes and peanuts.

Other foods containing profilin proteins are kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, melon, strawberry, soya, barley, walnut, lychee, lupin, apple, banana, date, cherry, almond, peach, pear, mustard, carrot, tomato and wheat.

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, tomato, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.


Resources

Websites

Anaphylaxis Campaign - Allergy to Vegetables

How to Recognize an Eggplant Allergy

Could you have a nightshade allergy?

Allergen Encyclopedia - Aubergine

Science Direct - Profilins


Articles and Journals

The diagnosis and management of allergic reactions in patients sensitized to non-specific lipid transfer proteins, 2021

Solanum melongena allergy (A comprehensive review), 2021

Identification, cloning, and immunological studies on a major eggplant (Solanum melongena L.) allergen Sola m 1: A new member of profilin allergen family, 2020

Recurrent anaphylaxis in patient allergic to eggplant – a Lipid transfer protein (LTP) syndrome, 2018

Aubergine and Potato Sensitivity with Latex Sensitisation and Oral Allergy Syndrome, 2013

Profilins: mimickers of allergy or relevant allergens? 2011

Higher Histamine Sensitivity in Non-atopic Subjects by Skin Prick Test May Result in Misdiagnosis of Eggplant Allergy, 2009

Clinico-Immunological Analysis of Eggplant (Solanum melongena) Allergy Indicates Preponderance of Allergens in the Peel, 2009

Cross-reactivity between fruit and vegetables, 2003



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.


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