Key Allergens

Avocado is in the Lauraceae family of plants which also includes plants like cinnamon. This family of plants are not usually associated with food allergies.

The main allergen found in avocado is called Pers a 1, this is a chitinase, which is a plant derived enzyme made by plants naturally to act as a defence against fungal attacks.

Avocado is not associated with oral allergy syndrome, but oral symptoms are linked with latex allergy due to the chitinase.

Food Intolerances

Food is moderate in sulphites Food is low in FODMAP Food is high in salicylates

Avocado can contain a moderate amount of sulphites when processed into a dip or guacamole. This is a food intolerance which is more common in asthmatics. An improvement in symptoms can be made with a change to a low sulphite diet.

Avocado is a low FODMAP food. FODMAP stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.

Avocado is a food high in salicylates. Salicylates have the potential to cause worsening of asthma, swelling, itching and hives as well as food intolerance symptoms in people who are sensitive to salicylates.

You can read more about Food Intolerances on the dedicated Food Intolerance Page.

Associated Syndromes

Avocado allergy has been linked to Latex Food Syndrome, which is caused by the body confusing the proteins it encounters in food to that of latex proteins to which it is already sensitised.

Avocado allergy has also been linked in recent years to FPIES - Food Protein Induced Enterocolitis Syndrome. This is a condition commonly linked with food sensitivity and intolerances in babies.

Cross Reactivity

Those with a sensitivity to chitinase may have linked allergies to foods which contain high levels of chitinase, like banana, chestnuts, corn (maize), kiwi, papaya, pomegranate and tomatoes.

These foods lists are not exhaustive, the most up to date information is on the Cross Reactivity Tool.



DermNet NZ - Latex Allergy

Allergen Encyclopedia - Avocado

Allergy information for: Avocado (Persea americana)

NY Allergy & Sinus Centers - Avocado

Healthline - Dealing with an Avocado Allergy

FODMAPedia - Avocado

ATP Science - Salicylate Foods

Articles and Journals

Anaphylaxis after Avocado ingestion in a patient located in the Rio Grande Valley, 2024

Food Protein Induced Enterocolitis Syndrome: A Culprit Food Analysis, 2023

Avocado allergy. Identification of a new allergen, 2023

Prevalence and Patterns of Latex Glove Allergy among Healthcare Workers in a Tertiary Care Center In South India - A Cross-Sectional Study, 2022

Avocado allergy. Identification of a new allergen, 2022

Non-IgE-mediated food allergy: Evaluation and management, 2021

Are Dietary Lectins Relevant Allergens in Plant Food Allergy? 2020

Three cases of delayed onset repetitive emesis after avocado ingestion, 2018

Clinical characterization of Chilean patients with IgE-mediated food allergy, 2018

Class I endochitinase containing a hevein domain is the causative allergen in latex-associated avocado allergy, 1999

Class I chitinases as potential panallergens involved in the latex-fruit syndrome, 1999

Cross-reacting allergens in natural rubber latex and avocado, 1995

Latex allergy: clinical features and cross-reactivity with fruits, 1994

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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