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Key Allergens

Latex Food Syndrome is also sometimes known as Latex Fruit Syndrome. When a person becomes sensitised to the allergens in latex they may also become sensitised to certain foods which contain similarly shaped proteins.

There are 15 allergens associated with allergy to latex plants. The plant involved in latex allergy Hevea brasiliensis , the rubber tree plant, have allergens called Hev b 6 which is a hevein and Hev b 11 which is a chitinase. These are the most likely culprits for severe latex allergy

Chitinase is the protein thought to cause most instances of Latex Food Syndrome.

Hevein is a related protein and may also have some role in the Latex Food Syndrome.

Hev b 8 in the rubber tree plant is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases, but it still has an important role in Latex Food Syndrome.

Cross Reactivity

Those with a sensitivity to chitinase may have linked allergies to foods which contain high levels of chitinase like avocado, banana, chestnuts, mango, corn (maize), kiwi, papaya, pomegranate, tamarind, cashews, beetroot, chard, spinach and tomatoes.

Chitinase allergens can also affect the airways and can be found in coffee, cockroaches and dust mites.

Hevein proteins are found in rubber trees (as a contact allergen) and in turnip (as a food allergen).

Profilin proteins are found in many foods including, in the top 14 foods, celery, peanut, soyabeans, walnut, lupin, almonds, mustard and hazelnut all contain profilin proteins.

Fruits and vegetables containing these proteins are kiwi, pineapple, chilli, melon, orange, strawberry, lychee, apple, banana, aubergine (eggplant), peach, pear, tomato, dates, cherry and carrot.

Profilin proteins are also found in barley, sorghum and wheat.

These food lists are not exhaustive, the most up to date information is available on the Cross Reactivity Tool.

You can download a Latex Food Syndrome Factsheet from the Allergy Resources Ko-fi Shop for just $0.50 (£0.40 or €0.45). This has up to date information on which foods contain latex linked allergens and what to avoid if you think you have Latex Food Syndrome.



DermNet NZ - Latex Allergy

Allergen Encyclopedia - Latex Allergy

Allergy Asthma Network - Latex Allergy

Latex-Fruit Syndrome and Class 2 Food Allergy

Articles and Journals

Molecular Basis of Plant Profilins’ Cross-Reactivity, 2023

Comprehensive Review on Banana Fruit Allergy: Pathogenesis, Diagnosis, Management, and Potential Modification of Allergens through Food Processing, 2022

Avocado allergy. Identification of a new allergen, 2022

Jackfruit Anaphylaxis in a Latex Allergic Non-Healthcare Worker, 2021

Natural rubber latex allergy, 2021

Symptoms and awareness of latex allergy among healthcare workers, 2020

Latex-fruit syndrome in Italian children and adolescents with natural rubber latex allergy, 2013

Diagnosis of latex allergy: the importance of hev B 11, 2012

Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy, 2011

Cross-reactivity between Ficus benjamina latex and fig fruit in patients with clinical fig allergy, 2003

In vivo sensitization to purified Hevea brasiliensis proteins in health care workers sensitized to natural rubber latex, 2003

Allergens and natural rubber proteins, 2002

Class I chitinases as potential panallergens involved in the latex-fruit syndrome, 1999

Hevein-like protein domains as a possible cause for allergen cross-reactivity between latex and banana, 1998

Latex allergy: clinical features and cross-reactivity with fruits, 1994

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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