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Key Allergens

Buckwheat is in the Polygonaceae family of plants. Other plants in this family include sea grapes, which are a coastal plant where the fruit is eaten or made into a jelly.

Buckwheat is not actually related to wheat as it is not a grass, but it produces grain like seeds which can be used to replace cereals.

Buckwheat does not contain any gluten, so is becoming a more popular ingredient and can be eaten by coeliacs.

There are two types of buckwheat defined on the WHO Allergen Database, common buckwheat and Tartarian Buckwheat.

Common buckwheat contains 4 food allergens. These include vicilin like proteins, also known as 7S seed storage proteins. Fag e 2 is a 2S seed storage protein. Common buckwheat also contains a hevein-like allergen, which is linked to Latex allergy. These allergens make buckwheat more like seeds than other cereals.

Tartarian buckwheat also contains a 2S seed storage protein and an oleosin protein, which are commonly found in nuts and seeds.

Food Intolerances

Food is low in FODMAP Food is low in salicylates Food is medium in lectins

Buckwheat is a low FODMAP food if eaten in small quantities. FODMAP stands for Fermentable oligosaccharides, disaccharides, monosaccharides and polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.

Buckwheat is a food low in Salicylates, so has the potential to cause gastrointestinal food intolerance symptoms in people who are sensitive to salicylates.

Buckwheat contains a moderate amount of lectins, another cause of food intolerance. Cooking foods with lectins makes them more digestible and can reduce the symptoms of food intolerance.

You can read more about Food Intolerances on the dedicated Food Intolerance Page.

Associated Syndromes

Due to the hevein allergen in common buckwheat is can be linked to Latex Food Syndrome.

Cross Reactivity

Other food containing 2S albumin seed storage proteins are brazil nuts, canola oil, cashew nuts, castor beans, chickpeas, cocoa, soya beans, fenugreek, flaxseed, garbanzo beans, hazelnuts, kiwi, lemon, mustard, peanut, pecan, pine nuts, pistachio, poppy seeds, pumpkin, quinoa, rapeseed, sesame seeds, sichuan pepper, sunflower seeds, swede, tangerins, turnips and walnuts.

Other foods containing 7S seed storage proteins not mentioned above are lupin, chia seeds, coconut, lentils, macadamia nuts, mung beans and peas.

Oleosin proteins are also found in hazelnuts, palm oil, peanuts, quinoa and sesame.

Read more about Grain Allergens and Pseudocereals.

These food lists are not exhaustive, the most up to date information is on the Cross Reactivity Tool.



Science Direct - Buckwheat

Allergen Encyclopedia - Buckwheat Allergy

Anaphylaxis Campaign - Buckwheat

Allergy information for: Buckwheat (Fagopyrum esculentum)

Asthma & Allergy Association - Can you be allergic to buckwheat?

Foods Matter - Salicylate Food Intolerance

Articles and Journals

Botanical Impurities in the Supply Chain: A New Allergenic Risk Exacerbated by Geopolitical Challenges, 2024

Bioactive compounds, health benefits, and industrial applications of Tartary buckwheat (Fagopyrum tataricum), 2023

Food protein–induced enterocolitis syndrome due to buckwheat: A case report, 2023

Predictor of buckwheat allergy in children based on challenge test results: a retrospective observational study in Japan, 2022

Identification of a Novel Major Allergen in Buckwheat Seeds: Fag t 6, 2021

Understanding buckwheat allergies for the management of allergic reactions in humans and animals, 2020

Characterization of 16-kDa major allergen with α-amylase inhibitor domain in tartary buckwheat seeds, 2018

Concomitant sensitization to legumin, Fag e 2 and Fag e 5 predicts buckwheat allergy, 2018

Buckwheat allergy: a potential problem in 21st century Britain, 2011

Immunological characterization and mutational analysis of the recombinant protein BWp16, a major allergen in buckwheat, 2008

Characterization of buckwheat 19-kD allergen and its application for diagnosing clinical reactivity, 2007

Molecular cloning of cDNA, recombinant protein expression and characterization of a buckwheat 16-kDa major allergen, 2006

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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