CEDAR POLLEN ALLERGY
Key Allergens
Cedar is a tree in the
Pinaceae family of plants. Other plants in this family include fir trees, pines and spruces. They are an important species in terms of pollen allergy as they release a large amount of pollen in response to cold fronts.
There are many different species and each contains different combinations of allergens, they are all airway allergens associated with pollen.
Most contain pectate lyase, an enzyme involved in pollen development.
Other allergens found in cedar pollen include
gibberellin proteins, polygalacturonase and
thaumatin proteins.
Cedar trees release their pollen Autumn to December in response to low temperatures. This varies by country. It is considered to have high allergenicity and due to the volume of pollen it can release it is sometimes referred to as 'Cedar Fever', referring to the hayfever (allergic rhinitis) it causes.
Associated Syndromes
An allergy to cedar pollen is strongly associated with seasonal allergic rhinitis (hayfever).
A cedar pollen allergy is also linked to asthma, rhinoconjunctivitis and atopic dermatitis.
Cross Reactivity
Other pollen containing pectate lyase include ragweed, wormwood, cypress, sunflower and juniper. Pectate lyase is also a food allergen found in almond.
Gibberellins are also found in cypress pollen. These proteins are more commonly linked to food allergens in foods like chilli, orange, cherry, apricot, peach and pomegranate.
Polygalacturonase is an allergen also found in cypress, olive, timothy grass, plane trees and thistles. It has been also found as a food allergen in papaya.
Thaumatin proteins are also found in cypress and olive. They are also found as food allergens in kiwi, pepper, apple, banana, cherry and peach.
Resources
Websites
Woodland Trust - Cedar
Allergy UK - Allergic rhinitis
Worcester Pollen Forecast
Allergy UK - Managing your asthma and your allergic rhinitis throughout the seasons
Allergen Encyclopedia - Cedar
Science Direct - Japanese Cedar
AAFA - Pollen Allergy
Articles and Journals
Increased allergic episodes induced by Japanese apricot following the Cupressaceae pollen season in adult patients mono-sensitized to Pru p 7, 2024
Current State of Japanese Cedar (Cryptomeria japonica D. Don) Pollen Information and Future Directions for Its Airborne Allergen Determination and Improved Pollen Monitoring, 2024
Investigation of the sensitization rate for gibberellin-regulated protein in patients with Japanese cedar pollinosis, 2022
Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study, 2021
Japanese cedar and cypress pollinosis updated: New allergens, cross-reactivity, and treatment, 2021
Oral immunotherapy with transgenic rice seed containing destructed Japanese cedar pollen allergens, Cry j 1 and Cry j 2, against Japanese cedar pollinosis, 2012
Glycoform Analysis of Japanese Cedar Pollen Allergen, Cry j 1, 2005
Transition from a Botanical to a Molecular Classification in Tree Pollen Allergy: Implications for Diagnosis and Therapy, 2004
Key pollen allergens in North America, 2003
Identification of mutations in the genes for the pollen allergens of eastern red cedar (Juniperus virginiana), 2001
Variable expression of pathogenesis-related protein allergen in mountain cedar (Juniperus ashei) pollen, 2000
Sensitivity to two major allergens (Cry j I and Cry j II) in patients with Japanese cedar (Cryptomeria japonica) pollinosis, 1995
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