There are 3 allergens associated with coffee allergy. Cof a 1 is a chitinase
protein. Chitinase proteins are usually associated with Latex Food Syndrome
, but in this case the allergen is an inhalant allergen and not a food allergen, so does not need to be avoided if suffering from this syndrome.
Cof a 2 and Cof a 3 are both metallothionein proteins. Again these are inhalant allergens and not food allergens and they are used in the plant to bind metals such as zinc.
Coffee is a low FODMAP food. FODMAP
stands for F
olyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.
Coffee beans are low in salicylates (decaffinated coffee is also considered to be low). Salicylates
have the potential to cause gastrointestinal food intolerance symptoms in people who are sensitive to salicylates.
You can read more about Food Intolerances
on the dedicated Food Intolerance Page.
Allergy to chitinase proteins has been linked to Latex Food Syndrome.
Coffee allergy has been linked to asthma, rhinoconjunctivitis and atopic dermatitis, especially in those who pick, pack or process coffee beans.
Other foods containing chitinase proteins are chestnuts, banana, avocado, pomegranate and maize. Other plants containing chitinases which are considered to be inhalant allergens are cockroaches and dust mites.
Note this food list is not exhaustive, the most up to date information is on the Cross Reactivity Tool.
Allergen Encyclopedia - Coffee
Caffeine Allergy & Coffee Intolerance: What You Need to Know
Do I Have a Coffee Allergy?
Healthline - FODMAP foods
ATP Science - Salicylate Foods
Articles and Journals
Is exposure to pollen a risk factor for moderate and severe asthma exacerbations? 2023
Study of prevalence of skin prick test positivity for food allergens in chronic urticaria patients attending a tertiary care center in South India, 2022
Airborne allergic contact dermatitis caused by coffee beans in a coffee roaster, 2021
Food allergy in displaced people from Mosul City, 2021
Anaphylaxis caused by sodium caseinate contained in canned coffee, 2020
Food allergy test in chronic urticaria adult patients: A cross sectional study, 2019
Anaphylaxis to coffee from a specific geographic region, 2018
Identification of two metallothioneins as novel inhalative coffee allergens cof a 2 and cof a 3, 2015
Cof a 1: identification, expression and immunoreactivity of the first coffee allergen, 2012
Coffee Anyone? Are You at Risk of Allergy? 2012
Helminthic infection as a factor in new-onset coffee allergy in a father and daughter, 2008
Let me know if you found any of these interesting or useful.
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