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Key Points

Lipid Transfer Proteins (LTP) are found in many types of plants. You may be allergic to all or some of the foods mentioned in the cross reactivity section.

LTP Syndrome can be confused with Pollen Food Allergy Syndrome (PFAS) as there is a crossover of common trigger foods. In general PFAS symptoms are less severe and give oral allergy type symptoms. Reactions to LTP are more severe and a reaction is elicited from foods that have been cooked.

The articles below all relate generally to LTP syndrome - please visit each food page for resources on specific foods.

To read more about the proteins themselves please visit the Lipid Transfer Protein page.

Cross Reactivity

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, millet, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

You can download a Lipid Transfer Protein Factsheet from the Allergy Resources Ko-fi Shop for just $0.50 (£0.40 or €0.45). This has up to date information on which foods contain Lipid Transfer Proteins and what to avoid if you think you have LTP Syndrome.

This food list above is not exhaustive, for the most up to date information visit the Cross Reactivity Tool.



British Dietetic Association - PFAS vs LTP Syndrome

Science Direct - Lipid Transfer Protein

Science Direct - Plant LTPs

Allergy UK - Lipid Transfer Proteins

Anaphylaxis UK - Lipid Transfer Proteins Syndrome

Articles and Journals

Food-dependent exercise-induced allergic reactions in Lipid Transfer Protein (LTP) hypersensitive subjects: new data and a critical reappraisal, 2024

Understanding of lipid transfer protein sensitization patterns and its clinical significance in children, 2024

A case of a 6-year-old boy diagnosed with lipid transfer protein syndrome using the ImmunoCAP and ImmunoCAP Immuno Solid-phase Allergen Chip, 2024

Clinical management of plant food allergy in patients sensitized to lipid transfer proteins is heterogeneous: identifying the gaps, 2023

Lipid transfer protein syndrome in a Northern European patient: An unusual case report, 2023

Lipid transfer protein allergy and anaphylaxis in children, 2023

Anaphylaxis across Europe: are pollen food syndrome and lipid transfer protein allergy so far apart? 2022

Recent Advances in Electrochemical Sensing Strategies for Food Allergen Detection, 2022

Lipid transfer protein allergy: A review of current controversies, 2022

Prevalence of sensitization to molecular food allergens in Europe: A systematic review, 2022

Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis, 2022

Lipid Transfer Protein Syndrome - an emerging allergy in non-mediterranean countries? 2021

Does the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins? 2021

The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area, 2021

Non-specific lipid-transfer proteins: Allergen structure and function, cross-reactivity, sensitization, and epidemiology, 2021

The diagnosis and management of allergic reactions in patients sensitized to non-specific lipid transfer proteins, 2021

Nickel allergy in lipid transfer protein sensitized patients: Prevalence and clinical features, 2020

Lipid Transfer Protein allergy in the United Kingdom: Characterization and comparison with a matched Italian cohort, 2019

Anaphylaxis caused by lipid transfer proteins: an unpredictable clinical syndrome, 2018

Stability of Allergens, 2018

How relevant is panallergen sensitization in the development of allergies?, 2016

Asymptomatic LTP sensitisation is common in plant-food allergic children from the Northeast of Spain, 2016

In patients with LTP syndrome food-specific IgE show a predictable hierarchical order, 2014

Lipid transfer protein syndrome: clinical pattern, cofactor effect and profile of molecular sensitization to plant‐foods and pollens, 2012

Molecular allergology in practice: an unusual case of LTP allergy, 2011

Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.

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