POLLEN FOOD ALLERGY SYNDROME
Key Allergens
This was previously called Oral Allergy Syndrome (OAS), the term was coined to define the symptoms. It has now been termed Pollen Food Allergy Syndrome (PFAS) more definitively as it mostly affects people who already suffer from pollen allergies and seasonal rhinitis due to cross reactivity.
In PFAS the body mistakes the shape of a protein that it is already sensitive to (a plant pollen) to a similarly shaped protein in certain fruits, vegetables, spices, herbs, and nuts.
The key allergen in PFAS is the pollen associated with the group of foods you are having symptoms from eating. It is most commonly associated with
birch tree pollen, the allergen is called
Bet v 1-like proteins.
If you are interested in which foods contain which allergenic proteins you can visit the
Food Allergy Tool Page.
You may have Pollen-Food Allergy Syndrome if you suffer from oral allergy symptoms to 3 or more of the foods mentioned in cross reactivity section.
Celery-Mugwort-Spice Syndrome is a sub-category of Pollen Food Allergy Syndrome where
profilin proteins are the sensitising proteins.
Cross Reactivity
The main two cross reactive proteins associated with Pollen Food Allergy Syndrome are Profilin and Bet v 1. Below are screenshots from the Cross Reactivity Tool showing which foods contain which allergen.
Foods containing Bet v 1
Foods containing Profilins
You can read more about any of these foods from the dedicated Food Allergy Index or you can download a Bet v 1 and Pollen Food Allergy Syndrome Factsheet from the
Allergy Resources Ko-fi Shop for just $0.90 (£0.69 or €0.82).
Resources
Websites
Allergy UK - Information and Advice
AAAAI - Oral Allergy Syndrome
Anaphylaxis Campaign
Dermnet NZ - Pollen Food Allergy Syndrome
Patient UK - Oral Allergy Syndrome
Articles and Journals
Pollen-Food Allergy Syndrome: From Food Avoidance to Deciphering the Potential Cross-Reactivity between Pru p 3 and Ole e 7, 2024
Allergen Component Testing: Key in Diagnosing Atypical Pollen-Food Allergy Syndrome, 2024
Pollen food allergy syndrome secondary to molds and raw mushroom cross-reactivity: a case report, 2024
Diagnosis and Management of Pollen-Food Allergy Syndrome to Nuts, 2024
Carrot-Induced Systemic Reaction: A Unique Presentation of Pollen-Food Allergy Syndrome in a Young Boy, 2023
Cross-reactive food and pollen allergens most commonly involved in oral allergy syndrome in adults with eosinophilic esophagitis, 2023
Anaphylaxis across Europe: are pollen food syndrome and lipid transfer protein allergy so far apart? 2022
BSACI guideline for the diagnosis and management of pollen food syndrome in the U, 2022
Clinical Relevance of Profilin Sensitization Concerning Oral Allergy Syndrome in Birch Pollen Sensitized Patients, 2022
Surveillance of pollen-food allergy syndrome in elementary and junior high school children in Saitama, Japan, 2022
Food allergy in early childhood increases the risk of oral allergy syndrome in schoolchildren: A birth cohort study, 2022
Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study, 2021
Pollen-related food allergy in children with seasonal allergic rhinitis, 2021
Heterogeneity of Pollen Food Allergy Syndrome in Seven Southern European Countries: the @IT.2020 Multicenter Study, 2021
Molecular approach to a patient’s tailored diagnosis of the oral allergy syndrome, 2020
Insights into pediatric pollen food allergy syndrome, 2020
Food cross-reactivity in patients with pollen allergies, 2020
Pollen-food allergy syndrome in children, 2020
Update on pollen-food allergy syndrome, 2020
Oral Allergy Syndrome, 2010
Let me know if you found any of these interesting or useful.
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