Nickel is a metal which is commonly used as a binding metal in jewellery, metal fastenings on clothing such as zips and buttons, cutlery and mobile phone casings.
Silver coins contain traces of nickel, occupational allergic dermatitis is common in people who work frequently with cash.
Nickel allergy has also been noted after transplantation surgery, mostly associated with hip and knee replacements and in dental procedures.
Nickel can also be found in foods if cooked with nickel plated cookware and traces are found in canned foods.
Nickel allergy is associated with allergic contact dermatitis.
Cross reactivity to chrome
is commonly seen in patients who are allergic to nickel.
DermNet NZ - Nickel Allergy
American Academy of Dermatology Association - Nickel Allergy
Allergy UK - Nickel Allergy
NHS - Contact Dermatitis
Articles and Journals
The Changes in Nickel and Chromium Ion Levels in Saliva with Fixed Orthodontic Appliances: A Systematic Review, 2023
New Insights and Evidence on “Food Intolerances”: Non-Celiac Gluten Sensitivity and Nickel Allergic Contact Mucositis, 2023
Nickel allergy is associated with a broad spectrum cytokine response, 2023
Is Allergy to Titanium Bone Fixation Plates a Problem?, 2022
The Toxicological Risk Assessment of Dermal Exposure of Patients Exposed to Nickel and Chromium due to Application of Ointments with Marjoram Herb Extract (Majoranae Herbae Extractum) Available in Polish Pharmacies, 2022
Contact allergy across the human lifespan, 2020
Experimental evaluation of nickel and cobalt release from tools and self-reported prevalence of nickel and cobalt allergy in the German hairdressing trade, 2020
Surgical explantation of atrial septal closure devices for refractory nickel allergy symptoms, 2019
Metal allergy in total-joint arthroplasty, 2018
Metal Allergy: Nickel, 2018
Nickel allergy following European Union regulation in Denmark, Germany, Italy and the U.K., 2013
Metal Allergy and Systemic Contact Dermatitis: An Overview, 2012
Prevalence of nickel and cobalt allergy among female patients with dermatitis before and after Danish government regulation: A 23-year retrospective study, 2009
Nickel allergy in the United States: A public health issue in need of a “nickel directive”, 2009
Relationship between nickel allergy and diet, 2007
The impact of various patient factors on contact allergy to nickel, cobalt, and chromate, 2006
Nickel release from coins, 2001
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