PSYLLIUM SEED ALLERGY
Key Allergens
Psyllium seeds (or Ispaghula) are derived from plants in the
Plantaginaceae family of plants. Other plants in this family include
English Plantain (also called Ribwort).
Psyllium seeds are used in medicines as a remedy for constipation, diarrhoea and to reduce cholesterol. They are used in foods as a thickener and in gluten free foods as a binding agent.
Allergic reactions to psyllium husk are more common in those who pick and process the plant.
Food Intolerances

Psyllium is a low FODMAP food when eaten in small quantities.
FODMAP stands for
Fermentable
oligosaccharides,
disaccharides,
monosaccharides
and
polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.
Psyllium is a food low in
salicylates. Salicylates have the potential to cause worsening of asthma, swelling, itching and hives as well as food intolerance symptoms in people who are sensitive to salicylates.
Psyllium is
lectin free. This is another cause of food intolerance. Cooking foods with lectins makes them more digestible and can reduce the symptoms of food intolerance.
You can read more about
Food Intolerances on the dedicated Food Intolerance Page.
Associated Syndromes
Psyllium husk or seeds are currently associated with allergic rhinitis. There are multiple studies showing that ground psyllium used in baking or as a laxative can have an effect on the workers that use them without them being ingested. These studies are linked at the bottom of the page.
Cross Reactivity
Psyllium is closely related to Ribwort/English Plantain, so if you are allergic to psyllium you may also be allergic to the pollen of this weed.
Note these food lists are not exhaustive, you can find the most up to date information on the Cross Reactivity Tool.
Resources
Websites
Allergen Encyclopedia - Psyllium
Science Direct - Psyllium Seed Husks
Healthline - Psyllium (Plantago ovata, Plantago isphagula)
Articles and Journals
Sorghum- and millet-induced anaphylaxis: A case report, 2024
Vegan diet—alternative protein sources as potential allergy risk, 2023
Anaphylactic Shock Due to Psyllium (Plantago ovate Seed) Allergy: A Case Report, 2022
Occupational inhalant allergy in food handling occupations, 2022
Occupational IgE-mediated psyllium allergy in contemporary gluten-free and vegan baking: A case of allergic rhinitis, 2021
Psyllium-associated anaphylaxis and death: a case report and review of the literature, 2003
Anaphylactic reactions to a psyllium-containing cereal, 1991
Let me know if you found any of these interesting or useful.
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