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COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND

COMPREHENSIVE ALLERGY RESOURCES FOR EVERYONE - THE TOP 14 ALLERGENS AND BEYOND
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CORN ALLERGY


Food Allergens

The terms maize and corn are often used interchangeably- maize is the name of the plant that grows corn, which is the product we eat.

There are 5 key allergens associated with maize, 3 of them are classified as airway allergens and 2 food allergens.

Zea m 8 is a chitinase protein. This is a plant derived enzyme made by plants naturally to act as a defence against fungal attacks.

Zea m 14 is a lipid transfer protein (LTP). This is considered to be a panallergen, causing allergic reactions over lots of different groups of foods.

Airway Allergens

Zea m 1 is a beta expansin protein. Expansins are proteins involved in cell wall expansion and modification. .

Zea m 12 is a profilin protein. This is another panallergen, found in both foods and pollens.

Zea m 25 is a thioredoxin protein which is in part responsible for cell growth.


Associated Syndromes

Corn/maize allergy has been seen in conjunction with allergies to other foods presenting as Latex Food Syndrome. This is due to the chitinase allergen. The body confusing the proteins it encounters in food to that of latex proteins to which it is already sensitised.

LTP's are a group of proteins which can cause more serious allergic reactions in patients, you may suffer from LTP Syndrome if you suffer IgE type allergy symptoms to foods mentioned in the cross reactivity section below.

Cross Reactivity

Those with a sensitivity to chitinase may have linked allergies to foods which contain high levels of chitinase like chestnuts, banana, avocados, papaya, pomegranate, kiwi and tomatoes.

Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.

Many different species of grasses contain the beta-expansin allergen, including rye, rice and maize.

Other plants containing profilin inhalant allergens are ragweed, wormwood, birch, sunflower, olive, plantain, poplar and oak. Profilins are also found as food allergens in kiwi, celery, peanut, chilli, watermelon, orange, hazelnut, melon, carrot, strawberry, soya, walnut, lychee, lupin, apple, cherry, almond, peach, pear, mustard, tomato and aubergine.

Thioredoxin is also common in moulds and wheat.



Resources

Websites

Science Direct - Expansins

Science Direct - Thioredoxin

Anaphylaxis Campaign - LTP Syndrome

Allergy information for: Maize, corn (Zea mays)

ACAAI - Corn Allergy

Corn Allergy: What Are the Symptoms?

NY Allergy & Sinus Clinic - Corn Allergy


Articles and Journals

Recent Surveys on Food Allergy Prevalence, 2020

Characterization of maize chitinase-A, a tough allergenic molecule, 2017

Cross-reactivity syndromes in food allergy, 2013

Maize food allergy: lipid-transfer proteins, endochitinases, and alpha-zein precursor are relevant maize allergens in double-blind placebo-controlled maize-challenge-positive patients, 2009

Maize food allergy: a double-blind placebo-controlled study, 2008

Detection of Some Safe Plant-Derived Foods for LTP-Allergic Patients, 2007

The expansin superfamily, 2005

The maize major allergen, which is responsible for food-induced allergic reactions, is a lipid transfer protein, 2000

Class I chitinases as potential panallergens involved in the latex-fruit syndrome, 1999

Latex allergy: clinical features and cross-reactivity with fruits, 1994



Let me know if you found any of these interesting or useful. If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.


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