ANGELICA ALLERGY
Key Allergens
Angelica is a plant in the
Apiaceae family of herbs. Other plants in this family include aniseed, celery, carrot, cumin, dill, parsley and parsnip.
It is not a commonly eaten herb, but is used in herbal medicines and as a flavour in some gins.
Other herb and spices contain
profilin and
Bet v 1 proteins, as a less commonly used herb there aren't any studies looking at the particular allergenic proteins in it, but it is likely that angelica does contain these allergens.
Like other herbs and spices angelica contain
furanocoumarins. These chemicals can get on the skin and in combination with ultraviolet light (sunlight) can cause a sunburn like rash. Furanocoumarins are found in higher concentrations in fresh herbs and are natural irritants which can cause allergic contact dermatitis. This is more common in occupations where you are frequently coming into contact with the food, like chefs, cooks, growers and pickers.
You can read more about other herbs and spices on the
Herbs and Spices page.
Food Intolerances
Angelica is a low FODMAP food.
FODMAP stands for
Fermentable
oligosaccharides,
disaccharides,
monosaccharides
and
polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.
Like many other herbs Angelica is a food high in
salicylates. Salicylates have the potential to cause worsening of asthma, swelling, itching and hives as well as food intolerance symptoms in people who are sensitive to salicylates.
You can read more about
Food Intolerances on the dedicated Food Intolerance Page.
Associated Syndromes
Angelica is linked to allergic contact dermtatitis and phytophotodermatitis as it contains furanocoumarin, a natural skin irritant in some people.
Cross Reactivity
If you are allergic to angelica you may also be allergic to closely related plants. Other plants in the
Apiaceae family of plants include aniseed, caraway seed, carrot, celery, coriander (cilantro), cumin, dill, fennel, lovage, parsley and parsnip.
Note these food lists are not exhaustive, you can find the most up to date information on the Cross Reactivity Tool.
Resources
Websites
DermNet NZ - Phytophotodermatitis
Science Direct - Angelica
Science Direct - Furanocoumarin
Web MD - Angelica archangelica
Articles and Journals
A Review of Phototoxic Plants, Their Phototoxic Metabolites, and Possible Developments as Photosensitizers, 2024
Angelica sylvestris L. (Apiaceae) of the Isle of Skye (Scotland): chemical composition of essential oil from the aerial flowering parts, 2023
Phytochemical Constituents, Folk Medicinal Uses, and Biological Activities of Genus Angelica: A Review, 2022
Botanical Sources, Chemistry, Analysis, and Biological Activity of Furanocoumarins of Pharmaceutical Interest, 2019
New allergens from spices in the Apiaceae family: anise Pimpinella anisum L. and caraway Carum carvi L., 2020
Relevance of pollen-specific IgE levels to the development of Apiaceae hypersensitivity in patients with birch pollen allergy, 2007
Two cases of apiaceae spice allergy, 2007
Characterization of allergens in Apiaceae spices: anise, fennel, coriander and cumin, 2006
Food allergy and IgE sensitization caused by spices: CICBAA data (based on 589 cases of food allergy), 2002
Spice allergy in celery-sensitive patients, 1991
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