RASPBERRY ALLERGY
Key Allergens
Raspberries are part of the
Rosaceae family of plants, many species of plants in this order are cultivated for their fruit, including apples, cherries, pears and almonds.
The two main allergens identified in raspberry are Rub i 1 and Rub i 3.
Rub i 1 is an allergen in the
Bet v 1 family, which can cause oral allergy syndrome.
Rub i 3 has been identified as a
Lipid Transfer Protein (LTP), but is not commonly linked to LTP Syndrome.
A study from 2008 showed raspberries contain
chitinase proteins. These are proteins associated with
Latex allergy.
Food Intolerances
Raspberries are a high FODMAP food.
FODMAP stands for
Fermentable
oligosaccharides,
disaccharides,
monosaccharides
and
polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.
Raspberry is a food high in
salicylates. Salicylates have the potential to cause worsening of asthma, swelling, itching and hives as well as food intolerance symptoms in people who are sensitive to salicylates.
You can read more about
Food Intolerances on the dedicated Food Intolerance Page.
Associated Syndromes
You may have
Pollen-Food Allergy Syndrome if you suffer from raspberry allergy with oral allergy symptoms to 3 or more of the foods mentioned in cross reactivity section.
You may have
LTP Syndrome if you suffer more severe allergic reactions to multiple foods mentioned in the cross reactivity section.
An allergy to chitinase is linked to
Latex Food Syndrome. Which is when a person is sensitised to latex through contact and later has oral allergy type reactions to food which contain similarly shaped proteins.
Cross Reactivity
If sensitised to birch tree pollen you may have Pollen Food Allergy Syndrome and may also react to apple, kiwi, pear, peach, plum, nectarine, apricots, cherries, tomato, celery, carrot, potato, parsnip, pepper, dill, cumin, peas, coriander, fennel, hazelnut, walnut, almonds, peanuts, lentils and beans
Common foods involved in LTP allergy include kiwi, strawberries, sunflower seeds, walnut, apple, mulberry, banana, pea, apricot, cherry, plum, almond, peach pomegranate, raspberry, tomato, grape, celery, peanut, asparagus, cabbage, broccoli, chestnut, lemon, tangerine, orange, hazelnut, lettuce, lentils, lupin, green bean, pear, mustard, wheat and maize.
Chitinases are also found in avocado, banana, cashew, chestnut, coffee, corn, grape, kiwi, mango, passion fruit, plantain, pomegranates and spinach.
Please note that none of these food lists are exhaustive. The most up to date information is on the Cross Reactivity Tool.
Resources
Websites
British Dietetics Association - Pollen Food and LTP Syndrome
Allergen Encyclopedia - Raspberry
Anaphylaxis Campaign - Allergy to Fruit
Allergy UK - Oral Allergy Syndrome
Patient UK - Food Allergy - Oral Allergy Syndrome
Healthline - FODMAP Foods
ATP Science - Salicylate Foods
Articles and Journals
Food intolerances, 2024
Respiratory hypersensitivity reaction related to ingestion of raspberry, 2023
Allergy to persimmon (Diospyros kaki): A Chitinase and Thaumatin like protein, two new identified allergens, 2023
Analysis of Protein Sequence Identity, Binding Sites, and 3D Structures Identifies Eight Pollen Species and Ten Fruit Species with High Risk of Cross-Reactive Allergies, 2022
The Interaction between Antioxidants Content and Allergenic Potency of Different Raspberry Cultivars, 2020
Overview of Plant Chitinases Identified as Food Allergens, 2014
Anaphylactic shock to raspberry, 2014
Screening and identification of putative allergens in berry fruits of the Rosaceae family: Technical challenges, 2009
Identification of four IgE‐reactive proteins in raspberry (Rubus ideaeus L.), 2008
Currant allergy and the Rosaceae-grass pollen allergy syndrome: a case report, 2007
Occupational asthma due to freeze-dried raspberry, 2003
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