CARROT ALLERGY
Key Allergens
Carrots are in the
Apiaceae family of plants. Other plants in this family are aniseed, celery, coriander, cumin, dill, fennel, parsley and parsnip.
Most people react to the main allergen in carrot, which is Dau c 1, it is homologous to the
Bet v 1 protein found in birch tree pollen which can cause oral allergy type symptoms to multiple fruits and vegetables.
Dau c 4 is a
profilin protein. These proteins are considered to be a panallergen and can cause issues over many groups of foods.
Dau c 5 is an isoflavone reductase protein involved in plant defense mechanisms.
Carrots also contain chemicals called
furanocoumarins, these can act as a contact allergen. When they come in contact with the skin it can become more sensitive to sunlight which can cause blistering. This is more common as an occupational allergy with people who pick, pack and process carrtots.
Food Intolerances
Carrot is a low FODMAP food.
FODMAP stands for
Fermentable
oligosaccharides,
disaccharides,
monosaccharides
and
polyols. Foods high in FODMAPs can cause symptoms of food intolerance, affecting the gastro intestinal system and this can be mistaken for a true IgE food allergy.
Carrot is a food low in
salicylates, so has the potential to cause gastrointestinal food intolerance symptoms in people who are sensitive to salicylates.
You can read more about
Food Intolerances on the dedicated Food Intolerance Page.
Associated Syndromes
You may have
Pollen-Food Allergy Syndrome if you suffer from carrot allergy with oral allergy symptoms to 3 or more of the foods mentioned in the cross reactivity section. There is a big crossover between foods containing Bet v 1 like proteins and those containing profilin proteins. Generally if you cook a food and it no longer causes symptoms then you are more likely to have Pollen Food Allergy Syndrome as the proteins are denatured quickly with heat.
Allergy to carrot is sometimes linked to
Celery-Mugwort-Spice Syndrome as the sensitising allergen is a profilin protein called Art v 4, these proteins are also sometimes also called Bet v 2 proteins.
There is a link between carrot and
Latex Food Syndrome. The plant involved in latex allergy
Hevea brasiliensis, the rubber tree plant, has an allergen called Hev b 8 which is a profilin protein. Those very sensitised to latex may have a contact allergic reaction from other foods or plants containing profilin proteins, there is less evidence of this than sensitisation to other latex linked proteins like hevein and chitinases.
Carotenaemia is a skin condition where the excessive consumpton of certain foods, including carrots, or nutritional supplements causes the skin to turn yellow or orange.
Cross Reactivity
If sensitised to birch pollen you may have Pollen Food Allergy Syndrome and may also react to apple, kiwi, pear, peach, plum, nectarine, apricots, cherries, tomato, celery, potato, parsnip, pepper, dill, cumin, peas, coriander, fennel, hazelnut, walnut, almonds, peanuts, lentils and beans.
If sensited to mugwort pollen you may have Pollen Food Allergy Syndrome and may also react to apple, celery, dill, parsley, fennel, coriander, cumin and sunflower seeds.
Other foods containing plant profilins are kiwi, pineapple, celery, peanut, chilli, watermelon, orange, hazelnut, melon, strawberry, soya, barley, walnut, lychee, lupin, apple, banana, date, cherry, almond, peach, pear, mustard, tomato, aubergine and wheat.
Other foods containing isoflavone reductase proteins are hazelnuts, olives and pears.
Resources
Websites
Allergen Encyclopedia - Carrot
Dermnet NZ - Carotenaemia
Healthline - Carrot Allergy
Allergy information for: Carrot (Daucus carota)
Anaphylaxis Campaign - Allergy to Vegetables
Healthline - FODMAP Foods
ATP Science - Salicylates Food
Articles and Journals
Food allergy outside the eight big foods in Europe: A systematic review and meta-analysis, 2024
Carrot-Induced Systemic Reaction: A Unique Presentation of Pollen-Food Allergy Syndrome in a Young Boy, 2023
Allergenicity and IgE Recognition of New Dau c 1 Allergens from Carrot, 2023
Prevalence and Patterns of Latex Glove Allergy among Healthcare Workers in a Tertiary Care Center In South India - A Cross-Sectional Study, 2022
Spectrum and frequency of food allergy in Kyiv`s adult citizens with allergic rhinitis: a cross-sectional study, 2022
Allergic reactions to emerging food allergens in Canadian children, 2021
Occupational Rhinoconjunctivitis Induced by Unusual Allergens of Carrot, 2020
Food Processing Does Not Abolish the Allergenicity of the Carrot Allergen Dau c 1: Influence of pH, Temperature, and the Food Matrix, 2020
Food cross-reactivity in patients with pollen allergies, 2020
Food allergen sensitization patterns in a large allergic population in Mexico, 2020
Carrot allergy: double-blinded, placebo-controlled food challenge and identification of allergens, 2001
Molecular characterization of Dau c 1, the Bet v 1 homologous protein from carrot and its cross-reactivity with Bet v 1 and Api g 1, 1999
Let me know if you found any of these interesting or useful.
If you spot an article or research that you think is interesting you can message me or tag me on Facebook or Twitter - links at the bottom of the page.